2024 Tsc1 antibody

Tsc1 antibody

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August undefined, 2024

WebFeb 16, 2024 · This is a Validated Antibody Database (VAD) review about human TSC1, based on 29 published articles (read how Labome selects the articles), using TSC1 antibody in all methods.It is aimed to help Labome visitors find the most suited TSC1 antibody. Please note the number of articles fluctuates since newly identified citations are added … WebMar 21, 2024 · In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (PubMed:12271141, 28215400, 35772404).Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity …

The tumor suppressor FLCN mediates an alternate mTOR pathway …

WebAug 24, 2012 · The endogenous interaction of TBC1D7 with the TSC1-TSC2 complex was confirmed in reciprocal immunoprecipitations with a panel of six unique antibodies to TSC1 or TSC2, along with an antibody raised against TBC1D7 (Figure 1 B), the specificity of which was confirmed through siRNA-mediated knockdown of TBC1D7 (Figure S1 E).TBC1D7 … Web"Phospho-Hamartin/TSC1 (Ser511) antibodies" comparison. At Proteintech, we pride ourselves on our antibody quality, customer service and transparency. As such, we are … heather m. wilmore dds

TSC1 Monoclonal Antibody (5C8A12) (37-0400) - Thermo …

WebThe regulation of the subcellular localization of phosphatase and tensin homologue (PTEN) is critical to its tumor-suppressing functions. Previously, we found that the activation of the phosphoinositide 3-kinase (PI3K)/Akt/mTOR/S6 protein kinase (S6K) cascade triggers the nuclear export of PTEN duri … WebFeb 5, 2024 · How activated B cells build biosynthetic pathways and organelle structures necessary for subsequent robust antibody secretion is still unclear. The dominant model holds that nascent plasma cells adapt to increased antibody synthesis by activating the unfolded protein response (UPR) under the control of the transcription factor Xbp1. WebNov 10, 2024 · Tsc1 was immunoprecipitated from HEK293 cell lysates using anti-Tsc1 antibody and immunoblotted with indicated antibodies to confirm chaperone, co-chaperone, and client protein interaction. IgG was used as control. FLAG-tagged Hsp90α N-, M-, and C-domains were transiently expressed and immunoprecipitated from HEK293 cells. movies about mount st helens

Loss of TSC1/TSC2 sensitizes immune checkpoint blockade in

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WebFeb 3, 2024 · Double labeling with Tsc1 (Hamartin) and H +-ATPase antibodies demonstrated remarkable colocalization in cyst epithelial cells in Tsc1 KO mice (Fig. 3B). Double labeling with Tsc1 and AQP-2 antibodies indicated the expression of Tsc1 in the majority of cells lining the cysts with few and distinct AQP-2–expressing (principal cells … WebImmunoprecipitation of TSC1 was performed on HAP1 cell lysates. Antibody-bead conjugates were prepared by adding 2 µg of TSC1 polyclonal antibody (Product # PA5 … heather m. whitneyWebInvitrogen Anti-TSC1 Polyclonal, Catalog # PA5-20131. Tested in Western Blot (WB) and Immunocytochemistry (ICC/IF) applications. This antibody reacts with Human, Mouse, Rat … heather m wilmore dds

"WebJul 25, 2005 · The polyclonal and monoclonal TSC1 antibodies were gifts of V. Ramesh (Massachusetts General Hospital, Boston, MA). Affinity-purified antibody against GST was prepared from anti-GST serum using GST immobilized on glutathione-Sepharose as an affinity matrix. The mouse monoclonal α-vinculin antibody was obtained from Upstate … " - Tsc1 antibody

Tsc1 antibody

WebAntibody was affinity purified using an epitope specific to TSC1 immobilized on solid support. The epitope recognized by A300-316A maps to a region between residue 1100 and the C-terminus (residue 1164) of human tuberous sclerosis 1 using the numbering given in Swiss-Prot entry Q92574 (GeneID 7248). WebTSC1 antibody; see all. Images. Western blot - Anti-TSC-1 antibody (ab200728) All lanes : Anti-TSC-1 antibody (ab200728) Lane 1 : HEK293T whole cell lysate Lane 2 : sp2/0 whole cell lysate Lane 3 : H9C5 whole cell lysate Predicted band …

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WebAnti-TSC1 antibodies are offered by a number of suppliers. This target gene encodes the protein 'TSC complex subunit 1' in humans and may also be known as Hamartin, LAM, truncated hemartin, and tuberous sclerosis 1 protein. Structurally, the protein is reported to be 129.8 kilodaltons in mass. Based on gene name, fly, ... WebFeb 25, 2024 · hamartin Antibody (C-8) is an IgG 2b κ mouse monoclonal hamartin antibody (also designated TSC1 antibody or TSC antibody) suitable for the detection of the hamartin protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. hamartin Antibody (C-8) is available as both the non-conjugated anti-hamartin antibody form, as well as …

WebTuberous sclerosis complex (TSC) is an autosomal dominant disorder that is due to inactivating mutations in TSC1 (also known as hamartin) or TSC2 (also known as tuberin). TSC is featured by benign tumors (hamartomas ... (TSC1) (clone 1B2-2A8) antibody (upper). Proteins were visualized using a goat anti-mouse-IgG secondary antibody conjugated to ... WebIn addition, the antipeptide antibody αPEP13h reacting with a C-peptide terminal of the Pmel17 protein identifies over 82% of the LAM cells in lung nodules, but HMB-45 identifies only 25%. 26 As LAM is such a rare condition, it is important to obtain a proper opinion from a specialist as early as possible and to discuss your individual case with an expert on the …

WebRabbit anti Human TSC1 antibody recognizes an epitope within the internal region of the 130kDa tumour suppressor protein, Tumour sclerosis complex 1 (TSC1). Mutation within … WebApr 11, 2024 · TSC1 and TSC2 are also involved in the G2/M transition of the cell cycle through their interactions with CDK1 and cyclin B1. TSC1 has also been shown to interact with Factin and ERM (EzrinRadixinMoesin) proteins, implying a role in the modulation of cell adhesion and morphology. Human TSC1 Antibody

WebJan 12, 2024 · CD11c Cre Tsc1 f/f mice were crossed with Raptor f/f mice to generate CD11c Cre Tsc1 f/f Raptor f/+ mice. Antibodies and reagents. The following antibodies for flow cytometry were from BD ...

WebMedium consistency between antibody staining and RNA expression data. Medium consistency between antibody staining and RNA expression data. WESTERN BLOT i Validation i. Uncertain i. Weak band of predicted size but with additional bands of higher intensity also present. ... TSC1-201. TSC1-203. TSC1-208. TSC1-212. TSC1-213. TSC1 … movies about mpdWebPolyclonal Antibody for studying Hamartin/TSC1. Cited in 74 publications. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously validated in-house, Hamartin/TSC1 Antibody (CST #4906) is ready to ship. heather m wilmoreWebTSC1 Antibody (OTI2B2), TA802012, from Invitrogen™. Species Reactivity: Human; Applications: Western Blot Compre TSC1 Mouse anti-Human, Clone: OTI2B2, liquid ... movies about mountain musicWebThis antibody binds to Yeast LCB2. Format: Liquid or Lyophilized: Storage: Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use: Purity > 90% was determined by SDS-PAGE: Purification: Purified with Protein A or G affinity chromatography: Cellular Localization: Endoplasmic reticulum; Other locations heather mycoskieWebInvitrogen Anti-TSC1 Polyclonal, Catalog # PA5-20130. Tested in Western Blot (WB) applications. This antibody reacts with Human, Mouse samples. Supplied as 100 µg … heather mycoskie divorceWebRabbit recombinant monoclonal mTOR (phospho S2448) antibody [EPR426(2)] - BSA and Azide free. Validated in WB, IHC, Dot and tested in Mouse, Human. heather mycoskie facebookWebTSC1 antibody (ABIN1955081). Validated for IHC, ELISA. Tested in Human. Order online. English ... Comparison List Basket Phone: +1 877 302 8632 Fax: +1 888 205 9894 (Toll-free) E-Mail: [email protected]. Home Antibodies ELISA Kits Primary Antibodies. Monoclonal Antibodies; Polyclonal Antibodies; Recombinant ... heathermxz