Tnt trial 乳癌
Webb30 apr. 2024 · The TNT Trial was designed to compare the activity of the standard of care microtubule-disrupting agent docetaxel with the DNA-crosslinking agent carboplatin. We … Webb20 okt. 2024 · The TNT trial (NCT00532727), a phase III, open label, randomised clinical trial compared carboplatin (C) with docetaxel (D) in patients with recurrent locally advanced or metastatic triple negative breast cancer (TNBC) or with recurrent locally advanced or metastatic disease in germline BRCA1/2 mutation carriers, irrespective of …
Tnt trial 乳癌
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Webb6 juni 2024 · Patients with triple-negative breast cancer (TNBC) and residual invasive disease (RD) after completion of neoadjuvant … Webb21 okt. 2024 · Background: In the TNT trial of triple negative breast cancer (NCT00532727), germline BRCA1/2 mutations were present in 28% of carboplatin responders. We assessed quantitative measures of structural chromosomal instability (CIN) to identify a wider patient subgroup within TNT with preferential benefit from …
Webb23 okt. 2024 · Many now consider a ’blanket’ TNT tri-modality approach as the standard of care, and indeed this strategy with 8 cycles is used in the NRG-GI002 Clinical Trial … Webb10 feb. 2024 · NRG-GI002: A phase II clinical trial platform using total neoadjuvant therapy (TNT) in locally-advanced rectal cancer (LARC)—Pembrolizumab experimental arm (EA) …
Webb28 juli 2024 · 対側乳がんの既往歴のある患者は、過去5年以内に最初の原発性乳がんの再発の証拠がない場合に適格です。 他の悪性腫瘍の病歴があり、少なくとも 5 年間無病 … WebbWe assessed the efficacy of carboplatin and another mechanistically distinct therapy, docetaxel, in a phase 3 trial in subjects with unselected advanced TNBC. A prespecified …
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Webb27 mars 2024 · 研究名称 / Scientific Title(Acronym). 乳癌患者の抗悪性腫瘍薬投与に伴う脱毛に対するPAX-15の群間比較試験. A Multicenter controlled trial of PAX-15 Hair Loss Prevention System with chemotherapy-induced alopecia in breast cancer patients in Japan. 平易な研究名称 / Public Title(Acronym). HOPE試験. rtd2525aWebb12 apr. 2024 · HR+/HER2-乳腺癌内分泌治疗——2024年度进展回顾及启示,肿瘤,危象,乳癌,乳腺癌,癌症患者, ... Azim H, et al. Primary results from the randomized Phase II RIGHT Choice trial of premenopausal patients with aggressive HR+/HER2− advanced breast cancer treated with ribociclib + endocrine therapy vs physician ... rtd2281wWebbMethods/design: TnT is a cluster-randomised feasibility trial conducted over 7 months with parallel qualitative and economic assessments. Colleges will be randomly allocated into … rtd2525arWebb9 nov. 2024 · 三陰性乳癌是指雌激素受體(er)、黃體素受體(pr)、第二型人類上皮生長受體(her2)的基因表達檢測皆為陰性的乳癌,也是致命性與復發率最高 ... rtd2 star warsWebb22 maj 2024 · TNT試験とは、トリプルネガティブ乳がん患者(N=376人)に対してカルボプラチン単剤療法を投与する群(N=188人)、またはドセタキセル単剤療法を投与す … rtd260cn 校正Webb27 aug. 2015 · 三阴性 乳腺癌 (triple negative breast carcinoma, TNBC)是一种特殊亚型的 乳腺癌 ,特指雌激素受体 (ER)、孕激素受体 (PR) 及人类表皮生长因子2 (HER2)三种受体均为阴性的 乳腺癌 。 TNBC 在西方人中发病率约占所有 乳腺癌 的12% ~ 17%。 此类型 乳腺癌 好发于40 岁以下的妇女,细胞分化差、具有高度侵袭性。 TNBC 对内分泌治疗及分子靶向 … rtd2555tWebb1 maj 2015 · TNT will be the first randomised trial to report the activity of platinum compared with standard chemotherapy within TNBC subtypes and in relation to … rtd2660h pdf