NettetCathepsin D is a lysosomal aspartic protease of the pepsin family (1). Human cathepsin D is synthesized as a precursor protein, consisting of a signal peptide (residues 1‑18), … Cathepsin B (CTSB) and L (CTSL) are cysteine proteases, and Cathepsin D (CTSD) is an aspartic protease 8. These cathepsins are major lysosomal proteases and are widely expressed in endosomes and ... Se mer In order to investigate the role of Ctsb, Ctsd and Ctsl in autophagy of the pancreas, we generated pancreas-specific Ctsb-, Ctsd- or Ctsl-deficient (CtsbΔPan, CtsdΔPan, CtslΔPan) mice using the Cre-loxP system. Pancreas … Se mer In order to investigate the autophagic activity in the pancreases of CtsbΔPan;CtsdΔPan, CtsbΔPan;CtslΔPan and … Se mer We compared the weight at one, four and eight months old between wild-type mice and CtsbΔPan;CtsdΔPan mice. No significant difference was noted between the weights at one and … Se mer
Mouse Anti-CTSB Monoclonal Antibody (CA10), Unconjugated
NettetAnti-mouse Cathepsin B antibody Microplate (12 x 8 wells) 1 unit. Avidin-Biotin-Peroxidase Complex (ABC) 1 x 130µl. Biotinylated anti-mouse Cathepsin B antibody 1 x 130µl. Lyophilized recombinant mouse Cathepsin B standard 2 x 10ng. Plate Seal 1 x 4 units. Sample Diluent Buffer Green Cap 1 x 30ml. TMB Color Developing Agent Amber … NettetMouse myeloma cell line, NS0-derived human Cathepsin B protein Arg18-Ile339 (pro) & Phe74-Ile339 (mature), both with a C-terminal 10-His tag Purity >95%, by SDS-PAGE under reducing conditions and visualized by silver stain Endotoxin level: 1.0 EU per 1 μg of the protein by the LAL method. N-terminal sequence Analysis tri cities tennessee weather
UniProt
NettetIn addition, it is possible that the localization of cathepsin B proteins to a particular location within the host cell might contribute to their ability to influence the number of bacteria in the host cell. We found that genomic deletion of cathepsin B in mice did not confer protection against the vacuolar-adapted pathogen S. Nettet10. apr. 2011 · Cathepsin B is a member of the papain-like family of cysteine proteases and is synthesized as a preproenzyme of 339 amino acids with a calculated molecular weight of approximately 38 kDa [reviewed in ( Kirschke et al. 1995; Mort and Buttle 1997 )]. Cathepsin B is a bilobal protein with its catalytic site located at the interface between … NettetAnti-Cathepsin B antibody, Mouse monoclonal is suitable for immunohistochemistry, western blot, indirect ELISA. AM EN. Applications Products Services Support. C6243; All Photos (1) C6243. Anti-Cathepsin B antibody, Mouse monoclonal. clone CB59-4B11, purified from hybridoma cell culture. All Photos (1) terminator genisys promotional images